Purity 99% Ibrutinib Powder

Name: China Purity 99% Ibrutinib Powder Suppliers, Manufacturers - Factory Direct Price - Jianfeng Chemical
Brand: Jianfeng
SKU: 141212190

CAS: 936563-96-1
MF: C25H24N6O2
Loss on drying: ≤1.0%
Purity: ≥99.0%
Melting point:153-158°C
Boiling point:715.0±60.0 °C(Predicted)
density:1.34
storage temp.:-20°C

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Description

Product introduction：

Ibrutinib powder is an antineoplastic agent that has been approved by the FDA since 2013 to treat chronic lymphocytic leukemia and mantle cell lymphoma in adults. It is an orally administered drug that works by blocking a certain enzyme, Bruton's tyrosine kinase, and preventing the growth and spread of cancer cells. Ibrutinib powder provides targeted, long-term relief from symptoms and has shown excellent efficacy and safety profile in many clinical studies.

10 characteristics about Ibrutinib powder:
1. It is a targeted, tailored therapy that can be easily administered orally.
2. It is a tyrosine kinase inhibitor that targets Bruton's tyrosine kinase.
3. It works by suppressing certain gene mutations in cancer cells that drive cancer growth and proliferation.
4. It provides long-term relief from symptoms in many chronic lymphocytic leukemia and mantle cell lymphoma patients.
5. It has a good safety profile with no major toxic side effects.
6. It can be used in combination with chemotherapy to decrease the needed dose of chemotherapy and mitigate side effects.
7. It can be used in combination with other drugs to boost its efficacy and widen its application.
8. It can be administered at home without special monitoring as long as the patient is closely monitored.
9. It helps relieve symptoms, maintain good quality of life, and prolong survival in cancer patients.
10. It increases the median overall survival rate in chronic lymphocytic leukaemia and mantle cell lymphoma patients.

Application:

1. Purity 99% Ibrutinib powder cas 936563-96-1 is used for Chronic graft-versus-host (cGVHD) disease after failure of one or more prior lines of systemic therapy.

2. Chronic lymphocytic leukemia (CLL) who have received at least one prior therapy.

3. Mantle cell lymphoma (MCL) who have received at least one prior therapy.

4. Marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy.

5. Waldenstrom's macroglobulinemia.

Certificate of analysis

Items	Standard		Results
Description	White To off-white powder		White powder
Solubility	Soluble in tetrahydrofuran, slightly soluble in methanol, dichloromethane or acetonitrile, slightly soluble in toluene, practically insoluble in water		Conforms
Identification	Should be accaordence with reference		Conforms
Water	≤1.5%		0.05%
Solvent residue	THF≤720ppm		400ppm
	Methylbenzene≤890ppm		not detected
	Methanol≤3000ppm		30ppm
	Dichloromethane≤600ppm		250ppm
	Ethyl acetate≤5000ppm		not detected
Residue on ignition	≤0.2%		0.07%
Heavy metals	≤20ppm		Conforms
Related substances	Single impurity	≤0.2%	0.04%
	Total impurity	≤2.0%	0.27%
Assay	97.0%—103.0%		100.4%

Our company

Jinan Jianfeng Chemical Co., Ltd

Jinan Jianfeng Chemical Co., Ltd. specializes in the research, development, and production of a wide range of products, including anticoagulants, antidepressants, antipsychotics, and other pharmaceutical intermediates. The company has a team of experienced researchers and technicians who work in state-of-the-art laboratories to ensure the quality and purity of its products.

Jinan Jianfeng Chemical Co., Ltd

Jinan Jianfeng Chemical Co., Ltd. is a leading manufacturer and supplier of pharmaceutical intermediates, APIs, and other fine chemicals. The company was founded in 2001 and is based in Jinan, China.

Jinan Jianfeng Chemical Co., Ltd

The company has obtained ISO9001:2015 certification, and its products are compliant with the international quality standards. Jinan Jianfeng Chemical Co., Ltd. exports its products to more than 50 countries and regions worldwide, including Europe, North America, South America, Asia, and Africa.

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