What Is JXL-069?
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Basic Information
| Product Name | JXL-069 |
| CAS Number | 2260696-63-5 |
| Molecular Formula | C20H11F6N3O2 |
| Molecular Weight | 439.32 g/mol |
| Compound Type | Mitochondrial Pyruvate Carrier (MPC) Inhibitor |
| Research Grade | Laboratory research use |
JXL-069 is a small-molecule mitochondrial pyruvate carrier (MPC) inhibitor developed during medicinal chemistry efforts to discover more potent MPC modulators. It was first described in research published in the Journal of Medicinal Chemistry in 2021.

JXL-069 Key Features
1. As a potent inhibitor of the mitochondrial pyruvate carrier, JXL-069 powder is used in mechanistic biology research.
2. JXL-069 is suitable for metabolic pathway research and can be used in structure-activity relationship (SAR) studies.
Suitable for mitochondrial biology research
JXL-069 raw material is widely cited in experimental metabolic research; Jinan Jianfeng Chemical can supply high-purity JXL-069.
JXL-069 is for research use only and has not been approved by the FDA or other relevant agencies for any other uses.
How Does JXL-069 Work?
Current studies indicate that JXL-069 selectively inhibits mitochondrial pyruvate carrier activity, reducing pyruvate transport into mitochondria.
As a result, researchers have observed changes in cellular metabolic pathways, including:
Altered mitochondrial pyruvate utilization
Increased reliance on glycolytic metabolism
Changes in lactate production
Modulation of cellular energy balance
Effects on metabolic signaling associated with stem cell activity
These observations have made JXL-069 a useful molecular tool for studying metabolic regulation in laboratory models.
Current Areas of Research
Like JXL-069, which is similar to hair follicle-related compounds such as ru58841, it is used in multiple research fields.
1. Hair Follicle Biology
2. Mitochondrial Metabolism Research
3. Stem Cell Metabolism
4. Drug Discovery Research
| English Name | CAS No. |
| jxl069 | 2260696-63-5 |
| Clascoterone/CB-03-01 | 19608-29-8 |
| Ru58841 | 154992-24-2 |
| Finasteride | 98319-26-7 |
| Minoxidil | 38304-91-5 |
| Dutasteride | 164656-23-9 |
If You Need Jxl069 Ingredient, Contact Us Now: sales01@pharmachemm.com
References
Liu X, et al. Development of Novel Mitochondrial Pyruvate Carrier Inhibitors to Treat Hair Loss. Journal of Medicinal Chemistry. 2021;64(4):2046–2063.
AOBIOUS. JXL069 (CAS 2260696-63-5) Product Information.
GLPBio. JXL069 Research Product Information.
Compliance Note (Google-friendly): This article is intended for scientific communication only. It describes published research findings and the characteristics of JXL-069 as a laboratory research compound. It does not claim that JXL-069 can diagnose, treat, cure, or prevent any disease, and it does not promote its use as a therapeutic product.










