Pure Baricitinib

Pure Baricitinib

CAS:1187594-09-7
MF:C16H17N7O2S
MW:371.42
EINECS:691-421-4
MOQ:1KG
Packing :25kgs/drum or 1kg/bag
Payment term:T/T,Paypal,Western Union

Description

What is Baricitinib?

Baricitinib is a disease-modifying therapeutic drug used to treat diseases caused by dysregulation of the immune system, such as rheumatoid arthritis and rheumatoid arthritis. It is also used to treat some autoimmune skin diseases and enteritis. Baricitinib belongs to a class of drugs called JAK inhibitors that reduce inflammation and the immune system's attack on normal tissues.

cas 1187594-09-7

Baricitinib application:

1. Rheumatoid arthritis (RA)
- Baricitinib is approved for the treatment of moderate to severe active RA in adults who have not responded well to or cannot tolerate conventional disease-modifying anti-rheumatic drugs (DMARDs).
- It can be used alone or in combination with methotrexate or other DMARDs.
- Baricitinib works by suppressing the activity of inflammatory cells and cytokines in the joints, reducing pain, stiffness, and swelling.

2. Atopic dermatitis (AD)
- Baricitinib is also being investigated for the treatment of AD, a chronic inflammatory skin condition characterized by itchy, red, and scaly patches.
- It is thought to work by blocking the signaling pathway of the Janus kinase (JAK) enzymes, which are involved in the immune response and itching sensation.
- Clinical trials have shown that baricitinib can improve the signs and symptoms of AD, including itch severity, sleep disturbance, and quality of life.

3. Systemic lupus erythematosus (SLE)
- Baricitinib is being studied as a potential therapy for SLE, an autoimmune disease that affects multiple organs and tissues, causing inflammation, damage, and pain.
- It is believed that baricitinib can modulate the immune system by inhibiting the production of pro-inflammatory cytokines and increasing the activity of regulatory T cells.
- Preliminary data from clinical trials have shown that baricitinib may reduce disease activity, skin rashes, and joint pain in SLE patients.

4. COVID-19
- Baricitinib has been suggested as a possible treatment for COVID-19, a respiratory illness caused by the SARS-CoV-2 virus.
- It has been proposed that baricitinib can reduce the inflammation and cytokine storm associated with severe COVID-19 by targeting JAK pathways.
- Several clinical trials are underway to evaluate the safety and efficacy of baricitinib in COVID-19 patients, either alone or in combination with other drugs such as remdesivir.

5. Psoriatic arthritis (PsA)
- Baricitinib is being investigated for its potential in treating PsA, a type of arthritis that affects people with psoriasis, a skin condition characterized by red, scaly patches.
- Baricitinib's mechanism of action is similar to other JAK inhibitors that have been approved for PsA treatment, such as tofacitinib and upadacitinib.
- Clinical trials are ongoing to determine the safety and effectiveness of baricitinib in PsA patients who have failed prior therapy.

 

Why choose us?

Jinan Jianfeng Chemical Co., Ltd. is a company headquartered in Jinan, China, which is specialized in the development, production and sales of pharmaceutical intermediates, APIs (active pharmaceutical ingredients), cosmetic raw materials and fine chemicals. The company has a state-of-the-art manufacturing facility and R&D center equipped with advanced technology and equipment to ensure high-quality products. Jinan Jianfeng Chemical Co., Ltd. has built a strong reputation in the industry with its dedication to quality, innovation and customer service. The company is committed to providing customers with safe and effective products that meet the highest quality standards and compliance.
Jinan Jianfeng Chemical specializes in providing raw materials for cosmetics, raw materials for analgesics, raw materials for antidepressants, raw materials for nootropic drugs, and various pharmaceutical intermediates. We continue to research and innovate, and provide our customers with high-quality and cheap products and high-quality services.

Our products are raw materials for semi-finished products, mainly sold to enterprises with processing capacity. Products are mainly sold to North America, Europe, South America, Australia and the Middle East and other countries.Thank you for your understanding! If you have any product questions, you can consult us, our business E-mail: sales01@pharchemm.com.

If you need, please feel free to send inquiry to sales01@pharchemm.com.

If there is a quality problem with the product or it does not pass the test, you can rest assured that we have an after-sales guarantee .

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Contact

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fax:0086-531-88113608

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Adress: Province Shandong, China

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