Inhibitor LOXO-292

Name: China Inhibitor LOXO-292 Suppliers, Manufacturers - Factory Direct Price - Jianfeng Chemical
Brand: Jianfeng
SKU: 141210784

Selpercatinib Inhibitor LOXO-292 cas 2152628-33-4 is an oral and selective investigational new agent that is being evaluated for the treatment of patients with cancers that harbor alterations in the RET kinase in the LIBRETTO-001 trial (NCT03157128).

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Description

Product introduction：

CAS: 2152628-33-4

MF: C₂₉H₃₁N₇O₃

Molecular Weight: 525.6

Synoyms: LOXO292, Selpercatinib, LY3527723, CPD2206

Description: Selpercatinib Inhibitor LOXO-292 cas 2152628-33-4 is an oral and selective investigational new agent that is being evaluated for the treatment of patients with cancers that harbor alterations in the RET kinase in the LIBRETTO-001 trial (NCT03157128).

Application: Treat advanced tumors, histiocytic disorders that have activating RET gene alterations. Selpercatinib block the growth of cancer cells that have specific genetic changes in an important signaling pathway (called the RET pathway) and may reduce tumor size.

Other chemical names: SELPERCATINIB, Selpercatinib(LOXO-292)

Certificate of analysis

TETS	STANDARD	RESULTS
Appearance	White to off-white powder	White powder
LC/MS	Conformity with the structure	Conform
NMR	Conformity with the structure	Conform
Loss on drying	≤0.5%	0.21%
Related substances by HPLC	Single impurity≤ 0.5% Total impurities≤1.0%	0.3% 0.42%
Assay	Calculated on anhydrous basis, 98.0%~102.0%	99.3%

Packing

Small quantity Inhibitor LOXO-292 cas 2152628-33-4 like 1kg will be packed in two sealed plastic bags and one foil bag, and large quantity Inhibitor LOXO-292 cas 2152628-33-4 like 25kg will be locked into fiber drums.

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