Osimertinib Powder
CAS:1421373-65-0
Specification : 99%
Appearance: White powder
Shelf life:2 years
Advantage:
Sample is Available
High purity, Top quality and best price
COA, HPLC, MSDS available
Certificate: ISO,GMP,CTC,SGS,CQC
Place of Origin: Shandong, China
Description
What Is Osimertinib Powder?
Osimertinib is a third-generation, orally available, irreversible, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. Upon oral administration, osimertinib covalently binds to and inhibits the activity of numerous mutant forms of EGFR, including the secondarily-acquired resistance mutation T790M, L858R, and exon 19 deletions, thereby preventing EGFR-mediated signaling. This may both induce cell death and inhibit tumor growth in EGFR-overexpressing tumor cells. EGFR, a receptor tyrosine kinase mutated in many tumor cell types, plays a key role in tumor cell proliferation and tumor vascularization. As this agent is selective towards mutant forms of EGFR, its toxicity profile may be reduced when compared to non-selective EGFR inhibitors which also inhibit wild-type EGFR.
| Product Name | Osimertinib |
| CAS NO. | 1421373-65-0 |
| Appearance | White powder |
| Purity | 99% |
| Acid value | 12.68±0.70(Predicted) |
| Density | 1.19±0.1 g/cm3(Predicted) |
| Application | AZD9291 intermediate; pharmaceutical intermediate; anti-tumor API; chemical raw material |
| Chemical structure |  |
| Usage | AZD9291 intermediate |
| Storage | Normal Temperature |
who choose us?
1.More than 10 years chemical exporting experience
We have produced chemical more than fifteen years., 80% products are for export .
More than 10 years chemical exporting experience. Good and stabilized factory price.
2.Strict quality control system
We has passed through the ISO9001:2015 Quality System Certificate, we have strict quality control system
3.Supply sample
Before order , we can send the sample for your testing . We ensure the quality is the same as bulk quantity .
one-stop solution
professional team
high quality
--Contact us via Email.
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--Description of order quantity.
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--The sales manager gives you a quote and sends you a contract.
--Delivery the same day after payment.
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