Dabigatran Etexilate Mesylate

After more than ten years of development, the company has established close cooperative relations with many domestic chemical research institutions and has a number of production bases. Production in strict accordance with ISO, GMP,FDA standards, products through strict factory testing, to ensure 100% qualified products.

Introduction of Dabigatran etexilate mesylate powder
Dabigatran etexilate mesylate powder is a novel anticoagulant drug used to prevent and treat blood clots in patients with atrial fibrillation, deep vein thrombosis, and pulmonary embolism.Dabigatran etexilate mesylate powder is a promising anticoagulant drug that offers several advantages over traditional anticoagulants. It has a fast onset of action, shorter half-life, and fewer interactions with other drugs, making it easier to manage and adjust the dosage.

Dabigatran etexilate mesylate Mechanism of Action
The active ingredient, dabigatran etexilate, is a prodrug that requires oral activation in the stomach, followed by absorption into the bloodstream. It then inhibits thrombin, a crucial enzyme involved in blood clotting, and thereby prevents the formation of new clots and the growth of existing ones.

 

 

 

Advantages over Other Anticoagulants
Dabigatran etexilate mesylate powder has several advantages over traditional anticoagulant drugs, such as warfarin. Firstly, it has a faster onset of action and provides rapid anticoagulation effects within a few hours of administration. Secondly, it has a shorter half-life (12-17 hours) compared to warfarin (up to 24-48 hours), making it easier to manage and adjust the dosage. Thirdly, it has fewer interactions with other drugs, foods, and alcohol, thus reducing the risk of adverse effects and complications.

Dabigatran etexilate mesylate Clinical Efficacy and Safety
Several clinical trials have demonstrated the efficacy and safety of dabigatran etexilate mesylate powder in various patient populations. For instance, the RE-LY trial showed that dabigatran was non-inferior to warfarin in preventing stroke and systemic embolism and had a lower risk of major bleeding events. The RE-MEDY and RE-SONATE trials also showed that dabigatran had a lower risk of major bleeding compared to warfarin and placebo, respectively.

Side Effects and Precautions
The most common side effects of dabigatran etexilate mesylate powder include gastrointestinal disturbances, such as dyspepsia, nausea, and diarrhea. Other potential adverse effects include bleeding, anemia, liver dysfunction, and allergic reactions. Patients with a history of bleeding disorders, renal impairment, or liver disease should be closely monitored while taking dabigatran.

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Why choose Jianfeng Dabigatran etexilate mesylate?

Jinan Jianfeng Chemical Co., Ltd. is a company headquartered in Jinan, China, which is specialized in the development, production and sales of pharmaceutical intermediates, APIs (active pharmaceutical ingredients), cosmetic raw materials and fine chemicals. The company has a state-of-the-art manufacturing facility and R&D center equipped with advanced technology and equipment to ensure high-quality products. If you need, please feel free to send inquiry to sales01@pharchemm.com.

If there is a quality problem with the product or it does not pass the test, you can rest assured that we have an after-sales guarantee .

Contact

Email:sales01@pharmachemm.com

fax:0086-531-88113608

Adress: Province Shandong, China

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