Citalopram Hydrobromide

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Citalopram hydrobromide (citalopram HBr) is an orally administered selective serotonin reuptake inhibitor (SSRI) with a chemical structure unrelated to that of other SSRIs or of tricyclic, tetracyclic, or other available antidepressant agents.
Citalopram HBr occurs as a fine, white to off-white powder. Citalopram HBr is sparingly soluble in water and soluble in ethanol.
The tablet is available as the brand-name drug Celexa. In Australia, the UK, Germany, Portugal, Poland, and most European countries, it is licensed for depressive episodes and panic disorder with or without agoraphobia. In Spain, it is also used for obsessive-compulsive disorder.

Oral: Adults once a day. The initial dose is 20 mg per day, which can be increased to 40-60 mg per day if a clinical need arises.
The dosage of patients over 65 years old was reduced by half (10-30 mg per day). Antidepressant treatment must last for an appropriate period of time. It takes 4 to 6 months for the manic-depressive disorder. If insomnia or severe inability to sit still occurs, sedatives should be supplemented in the acute phase. Children's clinical experience is unknown, please follow the doctor's advice.

The Patients who taking monoamine oxidase inhibitors should not use citalopram hydrobromide at the same time. Citalopram hydrobromide can be used after 14 days of discontinuation of the monoamine oxidase inhibitor. However, if a reversible monoamine oxidase inhibitor with a short half-life, such as moclobemide, is used, citalopram hydrobromide can be used after one day of withdrawal.

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