Citalopram Hydrobromide

Product Name:Citalopram hydrobromide
CAS:59729-32-7
MOQ:1KG
Shipping:The sameday shaipping

CitalopranHBr;1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrilehydrobromi;Citalopramhydrobromidesolution;CitalopramHBrSalt;1-[3-(DIMETHYLAMINO)PROPYL]-1-(4-FLUOChemicalbookROPHENYL)-1,3-DIHYDRO-5-ISOBENZOFURANCARBONITRILEHYDROBROMIDE;1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrilehydrobr;CITALOPRAMHBR;(+/-)-CITALOPRAMHYDROBROMIDE

CAS No.: 59729-32-7

Molecular formula: C20H22BrFN2O

Molecular weight: 405.3

EINECS Number: 261-890-6

overview

Citalopram hydrobromide is a highly selective 5-hydroxytryptamine (5-HT) uptake inhibitor with antidepressant effects. The advantage of this drug is that it has no inhibitory effect on cholinergic muscarinic receptors, histamine receptors and alpha-adrenergic receptors. Because if these receptors are inhibited, many side effects caused by antidepressants will occur, such as dry mouth, sedation, orthostatic hypotension, etc. Citalopram hydrobromide is equally effective in patients with endogenous and non-endogenous depression, and its antidepressant effect is usually established after 2-4 weeks. Citalopram hydrobromide does not affect the cardiac conduction system and blood pressure, which is especially important for elderly patients. In addition, citalopram hydrobromide does not affect the blood, liver and kidney systems. The rare side effects and minimal sedative properties make it particularly suitable for long-term treatment. Neither causes weight gain nor enhances the effects of alcohol.

Adverse reactions

Side effects are usually rare, mild, and short-lived. The most common adverse reactions were: nausea, increased sweating, decreased salivation, headache and decreased sleep time. It is usually evident during the first or second week of treatment and generally disappears as the depression improves. Seizures have been observed in rare cases. In patients with pre-existing bradycardia, bradycardia can complicate treatment.

biological activity

CitalopramHBr (NitalapramHBr, PrepramHBr, BonitroleHBr, Lu10-171HBr) is an antidepressant and a selective serotoninreuptake inhibitor commonly used in oral route with IC50 of 1.8nM.

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