API 99%CAS 2016-88-8 Amiloride Hydrochloride Pharmaceutical Raw Material
API Nepafenac powder cas 78281-72-8 is a non-steroidal anti-inflammatory drug indicated for the prevention and treatment of inflammation and pain associated with cataract surgery.
Description
brief introdution
Nepafenac is a novel ocular non-steroidal antipyretic, analgesic and anti-inflammatory drug (NSAIDs). Nepafenac is used to treat eye pain and inflammation caused by cataract surgery. Compared with traditional NSAIDs, the chemical structure of Nepafenac is favorable for the drug to rapidly penetrate the cornea and distribute at its target site. Therefore, it is helpful to reduce the accumulation of drugs on the surface of the cornea, reduce the occurrence of complications on the surface of the eye, and has the advantages of strong penetration, strong targeting effect and small toxic and side effects.
Parameter of Nepafenac
| Product Name | Nepafenac |
| CAS Number | 78281-72-8 |
| Chemical Formula | C15H14N2O2 |
| Appearance | White powder |
| Grade | Pharmaceutical grade |
| Purity | 99% |
| Shelf Life | 2 years |
Function Of Nepafenac
Nepafenac, when administered via the eye, rapidly passes through the cornea and is converted to amifenic acid (an NSAID) by hydrolases in the eye tissue; Amifenic acid plays an anti-inflammatory and analgesic role by inhibiting prostaglandin H synthetase (cyclooxygenase) and blocking the synthesis of prostaglandin. As is well known, prostaglandins are mediators that cause inflammation in the eye, leading to breakdown of the blood-aqueous barrier, vasodilation, increased vascular permeability and leukocyte chemotactic, etc. In addition, prostaglandins can also contract the iris sphincter through non-cholinergic mechanisms, leading to the constriction of the eyes during and after ophthalmic surgery. When administered via the eye, NSAIDs inhibit the synthesis of prostaglandins in the iris, ciliary body, and conjunctiva, thereby preventing eye inflammation and reducing associated pain.
Certificate Of Analysis
|
Items |
Standards |
Results |
|
Appearance |
Yellow or light yellow crystalline powder |
Conforms |
|
Loss on drying |
≤0.5% |
0.20% |
|
Related substances |
Individual impurity: NMT 0.5% |
0.05% |
| Total impurities: NMT 1.0% | 0.08% | |
|
Sulphated ash |
≤0.1% |
0.06% |
|
Heavy metals |
≤20ppm |
Conforms |
|
Assay |
98.5%~101.5% |
99.3% |
Packing & Shipping & Delivery
With years of experience in this field, we have a highly professional logistics team ensuring fast and secure delivery. Orders can be shipped on the same day payment is received. Our products are sold simultaneously across multiple channels, both domestically and internationally, online and offline.
Packaging:
Powder: Inner packaging options include PE bags, glass bottles, or PTFE bottles, with an outer layer of aluminum foil bag.
Bulk orders: Fiber drums or steel drums.
Custom packaging is also available.
Payment Options:
T/T, PayPal, Visa, L/C, Western Union, or tailored according to your requirements.
Shipping:
We ship via UPS, TNT, EMS, FedEx, and other carriers. Depending on your location, products will be safely cleared and delivered to your doorstep within 3–7 days in Europe and the United States.
Conpany profile
Best Supplier For Nepafenac In China
The Products Comply With International Standards Such As USP, EP, Gmp, ISO, FDA, Etc., Accept Odm/oem Service, Undergo Strict Quality Testing Before Leaving The Factory. There Is One R&d Center And Three Pharmaceutical And Chemical Plants.
We Are Committed To Providing You With The Most Competitive Prices To Ensure You Stand Out In The Market.
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FAQ
Q: What are the common applications of Nepafenac Powder?
A: Nepafenac Powder is primarily used as a pharmaceutical raw material for the development and manufacture of ophthalmic formulations.
Q: How do you ensure the quality of Nepafenac Powder?
A: The company has implemented a strict quality control system to ensure that all of its products meet or exceed the highest international standards. The company's quality control department is responsible for testing and analyzing each batch of products to ensure that they are of the highest quality.
Q: Can I get some samples?
A: Yes.
Q: What about after-sale service?
A: We promise to reissue free of charge if there is any problem.
Q: Which kind of payment terms do you accept?
A: For small order,you can pay by T/T, Western Union or Paypal, commercial order by T/T to our company account.
Q: How long will it take to receive the parcel?
A: The time is 5-7 days for the US market and 10-15 days for the others.
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