
Crisaborole Raw Powder
Crisaborole is a phosphodiesterase- 4 (PDE4) inhibitor that was approved by the USFDA for the treatment of mild to moderate atopic dermatitis (AD) in patients aged two years and older
CAS: 906673-24-3
MF: C14H10BNO3
MW: 251.05
EINECS: 250-635-4
MOQ:1KG
Shelf life:2 years
Advantage:
Sample is Available
Top quality and best price
COA, HPLC, MSDS available
Certificate: ISO,CTC,SGS,CQC
Place of Origin: Shandong, China
Description
Brief Introduction
Crisaborole is a phosphodiesterase- 4 (PDE4) inhibitor that was approved by the USFDA for the treatment of mild to moderate atopic dermatitis (AD) in patients aged two years and older. The drug, which was developed by Anacor Pharmaceuticals and later acquired and marketed , is delivered as a 2% ointment, which is applied topically. The unique employment of boron within the chemical structure of the drug is designed to enable selective engagement of PDE4 (an enzyme involved in the conversion of cAMP into AMP, which signals for downstream inflammatory events), effective penetration of the drug through human skin, and rapid clearance to limit systemic circulation.

Parameter Of Crisaborole
|
Product Name |
Crisaborole |
|
Application |
Industrial use |
|
CAS No. |
906673-24-3 |
|
Molecular formula |
C14H10BNO3 |
| MW | 251.05 |
|
Einecs |
250-635-4 |
|
Appearance |
White powder |
|
Purity |
99% |
|
Shelf Life |
2 Years |
Function And Uses
As a phosphodiesterase 4 (PDE4) inhibitor, crisaborole works by inhibiting the PDE4 enzyme, which helps decrease the production of inflammatory cytokines that cause the symptoms of atopic dermatitis.
Certificate of Analysis
| Batch No. | JF260602 | Quantity | 600kg |
| Mfg. Date | Jun. 02, 2026 | Package | As required |
| Rep. Date | Jun. 05, 2026 | Exp. Date | Jun. 01, 2028 |
| Items | Standards | Results | |
| Appearance | White or off-white solid powder | Complies | |
| Identification | By IR | Complies | |
| By HPLC | Complies | ||
| Solubility | Soluble in glycol | Complies | |
| Loss on Drying | ≤ 1.00% | 0.55% | |
| Residual Solvents | ≤3000ppm | ND | |
| ≤5000ppm | 4000ppm | ||
| Related Substances | Any single impurity: ≤0.30% | 0.10% | |
| Total Impurities: ≤1.00% | 0.28% | ||
| Assay (HPLC basis on drying) |
98.0%~102.0% | 99.85% | |
| Reference Standard | In-house Standard | ||
| Conclusion | The product complied to In-house standard. | ||
| Storage | Preserve in tight,light-resistant containers in a cool place | ||
Products Description
Having been engaged in this field for years, we have sophisticated and professional logistics department, which can guarantee safe and speedy delivery. The product can be shipped on the same day of payment. Simultaneous sales in multiple channels at home and abroad, online and offline.
| Package |
Powder: PE bag, glass bottle, or PTFE bottle for inner packing, and aluminum foil bag for outer packing. We can customize the packing according to customer's requirement. Bulk order: Fiber drum or steel drum. |
| Payment options | T/T,Paypal,L/C,Western Union,or according to your needs. |
Transportation |
UPS,TNT,EMS,Fedex,and so on.According to your location.By air or sea in large quantities. |


Our Advantage
JINAN JIANFENG CHEMICAL CO.,LTD--Our company was established in 2011. Since then, we have more than 10 experience in production, R&D and export. It participates in international and domestic exhibitions every year.The company has scientific research department, production department, quality inspection department, sales department, so we have absolute confidence in product quality and can provide COA and other documents.
Our services
♦ Competitive prices and high quality products
♦ A dequate inventory and products will be shipped out asap.
♦ Quick and clear response to customers questions.
♦ Comfortable conversation and easy talk
Our address
Building 2, Jigao Big Data Industry Center, No. 879, Shunhua Road Street, Gaoxin District, Jinan, Shandong Province

If there is a product quality problem, if the test is unqualified, there is after-sales guarantee, we can return and exchange the product free of charge, so that you have no worries.



FAQ
Q1: What is the mechanism of action of Crisaborole?
Crisaborole may work by inhibiting phosphodiesterase-4 (PDE-4), which can help increase intracellular cyclic adenosine monophosphate (cAMP) levels. This pathway is associated with the regulation of inflammatory responses in skin-related conditions.
Q2. What are the main applications of Crisaborole?
Crisaborole is mainly used as an active pharmaceutical ingredient (API) for topical dermatological formulations. It is commonly associated with research and product development related to skin care and inflammatory skin conditions.
Q3: How long will it take to receive the parcel?
3 days for the US market; 4-6 days for the others.
Q4: Can I order a sample of Crisaborole before bulk purchase?
Yes. Samples are available for quality evaluation before bulk orders. Customers can confirm product specifications and testing requirements in advance.
Q5: Are you a manufacturer of Crisaborole powder (CAS 906673-24-3)?
Yes, we are a professional manufacturer and supplier of Crisaborole powder. We provide high-quality raw materials with strict quality control, batch consistency, and supporting documents such as COA and testing reports. Bulk supply and customized packaging services are available for global customers.
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