Brigatinib Powder

 

Brigatinib is an oral small-molecule targeted therapy that has been developed for the treatment of advanced or metastatic ALK-positive non-small cell lung cancer (NSCLC). As a tyrosine kinase inhibitor, Brigatinib may help inhibit signaling pathways associated with abnormal ALK proteins, which are involved in tumor cell growth and proliferation.

 

Product Name	Brigatinib
Appearance	white powder
cas	1197953-54-0
MF	C29H39ClN7O2P
MW	584.09
EINECS	1592732-453-0
Assay	99%
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

 

 

Brigatinib is a targeted small-molecule compound that has been studied for its role in inhibiting abnormal ALK-related signaling pathways. As an ALK tyrosine kinase inhibitor (TKI), it may help regulate cellular processes associated with ALK activation, including pathways involved in cell growth, proliferation, and survival.

 

 

Brigatinib works by binding to and inhibiting the kinase activity of anaplastic lymphoma kinase (ALK) and certain related tyrosine kinases. By blocking abnormal ALK signaling, Brigatinib may interfere with downstream pathways involved in uncontrolled cell proliferation and tumor cell survival. It has also been investigated for its activity against specific ALK mutations that may contribute to resistance to other ALK inhibitors.

 

 

Product name	Brigatinib	Manufacture date	2026.6.15
Batch number	JF260616	Analysis date	2026.6.16
Batch quantity	150kg	Expiry date	2028.6.15

Item	Specification	Result
Appearance	White crystalline powder	Conforms
Specification	≥99.0%	Conforms
Identification	By IR	Conforms
	By HPLC	Conforms
Solubility	Soluble in DMF, sparingly soluble in THF,  very slightly soluble in ethanol, insoluble in water	Conforms
Polymorphic form	Polymorphic form 1	Conforms
Melting point	211-216℃	212.8-214.9℃
Heavy metals	≤20ppm	Conforms
Water content	≤0.5%	Conforms
Residue on ignition	≤0.2%	0.09%
Related substances	Any single impurity ≤0.1%	0.06%
	Total impurities ≤1.0%	0.16%
Particle size	D90<100μm	Conforms
Microbial
Total microbacterial count	≤1000cfu/g	Conforms
Yeast&Mould	≤100cfu/g	Conforms
Escherichia Coli presence	Negative	Conforms
Salmonella	Negative	Conforms
Staphylococcus	Negative	Conforms
Conclusion	Conforming to Enterprise Standard

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Packing:

1. Weight <1kg ---- Fluorinated bottle

2. 25kg ---- Plastic bucket

3. 180- 200kg ---- Drum

P.S.: we accept packaging customization.

Shipping:

We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg.

Shipping details & shipping documents will be provided and sent to customers as long as it is ready.

We keep tracking the shipment until clients well received.

After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safely and efficiently.

Delivery:

We have large quantity raw powder in stock, normally could ship out within 3 working days.

For rush delivery, please contact our sales team for particular arrangement.

 

 

What is the mechanism of action of Brigatinib?
Brigatinib works by inhibiting the kinase activity of anaplastic lymphoma kinase (ALK) and certain related kinases. This inhibition may help regulate downstream signaling pathways associated with cell proliferation and survival.

 

Is Brigatinib an API?
Yes, Brigatinib is classified as an active pharmaceutical ingredient (API). It is the active component used in the formulation of the approved drug Alunbrig.

 

What products can you supply?

A: We mainly supply pharmaceutical raw materials, APIs and pharmaceutical intermediates. We provide a wide range of high-purity powders for pharmaceutical, research, and industrial applications.

 

What is the delivery lead time?

A: The delivery time is usually around 3–5 working days after payment confirmation. We cooperate with reliable international logistics partners, including DHL, FedEx, and UPS, to provide efficient and secure shipping solutions.

 

How long does it take to receive the parcel?

A: Delivery time depends on the destination and shipping method. For most international shipments, delivery usually takes about 3–5 days to the United States and approximately 3–7 days to other regions.

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