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Aprocitentan Powder

Aprocitentan powder is an endothelin receptor antagonist that can lower blood pressure, protect the inner lining of blood vessels, and reduce the occurrence of arteriosclerosis.
CAS:1103522-45-7
MF:C16H14Br2N6O4S
MW:546.19
Shelf life:2 years
Advantage:
Sample is Available
Top quality and best price
COA, HPLC, MSDS available
Certificate: ISO,SGS
Place of Origin: Shandong, China

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Description

Description of Aprocitentan Powder

It is a drug that demonstrates groundbreaking potential in the field of cardiovascular diseases, particularly in the treatment of refractory hypertension.

Aprocitentan Powder

Parameter of Aprocitentan Powder

Product Name	Aprocitentan Powder
CAS	1103522-45-7
MF	C16H14Br2N6O4S
MW	546.19
Solubility	Chloroform (Slightly, Heated), Methanol (Slightly, Heated)
Form	Solid
Pka	13.56±0.60(Predicted)
Color	White to Off-White

Function

It helps alleviate vascular contraction by precisely blocking related signaling pathways, thereby playing a positive role in blood pressure regulation and the maintenance of functions of important organs such as the kidneys. Clinically, it is mainly used for the treatment and management of specific types of cardiovascular or renal diseases.
The selective binding mechanism of this drug ensures that it acts on key pathological links while minimizing non-specific effects on other receptor subtypes, which is crucial for improving treatment efficacy and reducing potential adverse reactions. Aprocitentan helps restore vascular function balance by targeting the renin-angiotensin-aldosterone system (a key regulatory pathway for cardiovascular and renal homeostasis in the human body), and protects the structural and functional integrity of target organs.

cOA Certificate Of Analysis

Product Name	Aprocitentan	CAS No.	1103522-45-7
Batch No.	JIANFENG-20250821	Manufacturing Date	2025/8/21
Expiry Date	2027/8/20	Analysis date	2025/8/21
Report date	2025/8/24	Country of Origin	CHINA
ITEM	SPECIFICATION	RESULT
Appearance	White Powder	Complies
Identification	Retention time matches reference standard	Complies
Assay (HPLC)	98.0% - 102.0%	99.86%
Water Content (Karl Fischer)	≤ 2.0%	1.36%
Residue on Ignition	≤ 0.1%	< 0.05%
Sulfated Ash	≤ 0.1%	< 0.05%
Heavy Metals (as Pb)	≤ 20 ppm	< 10 ppm
Microbial Limits - Total Plate Count	<1000cfu/g	<100cfu/g
Microbial Limits - Yeast & Moulds	<100cfu/g	<10cfuv/g
Microbial Limits - E.Coli	Negative	Negative
Microbial Limits - Salmonella	Negative	Negative
Conclusion: Conform with enterprise specification.(Based on USP, EP,ChP)

Packing & Shipping & Delivery

Packing:

1. Weight <1kg ---- Fluorinated bottle

2. 25kg ---- Plastic bucket

3. 180- 200kg ---- Drum

P.S.: we accept packaging customization.

Shipping:

We ship goods via DHL, Fedex, UPS, TNT, China post, NL Post and other couriers, weight from 10g to 1000kg.

Shipping details & shipping documents will be provided and sent to customers as long as it is ready.

We keep tracking the shipment until clients well received.

After years export shipping experience, with professional and experienced cooperated forwarders, we ensure that goods can be delivered in multiple ways safetly and efficiently.

Delivery:

We have large quantity raw powder in stock, normally could ship out within 3 working days.

For rush delivery, please contact our sales team for particular arrangement.

shipping

Our Advantage

Our company was established in 2011. Since then, we have over ten years of production, research and export experience. The company has a research department, a production department, a quality inspection department and a sales department. We offer high-quality aprocitentan powder and we have absolute confidence in the product quality and can provide documents such as COA.
If there are any quality issues with the products and the tests are not passed, we offer a warranty service. We can provide free returns and exchanges to ensure you have no worries.

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