Lurasidone Impurity 49

What is Lurasidone intermediate?

Lurasidone intermediate, also known as 3-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]benzamide, is a chemical compound with the CAS number 46022-05-3. This intermediate is part of the synthesis of lurasidone, a medication used to treat schizophrenia and depression.

Lurasidone intermediate is a white to off-white crystalline powder that is soluble in organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO). It has a molecular formula of C18H19N3O2S and a molecular weight of 341.43 g/mol.

The production of lurasidone intermediate typically involves the reaction between 4-(1,2-Benzisothiazol-3-yl)piperazine and 3-bromo-benzoic acid, followed by the coupling with N-benzyl-4-methoxy-benzenesulfonamide. The reaction yields the final compound as a solid that can be purified using recrystallization techniques.

Lurasidone intermediate Application:

Lurasidone intermediate has a variety of applications in the pharmaceutical industry. As the building block for the synthesis of lurasidone, it plays an essential role in the production of this medication. Lurasidone is an atypical antipsychotic that acts as a selective dopamine D2 antagonist and a serotonin 5-HT2A receptor antagonist. It has been shown to be effective in treating both positive and negative symptoms associated with schizophrenia and depression, making it a valuable medication for patients with these conditions.

Additionally, the intermediate can be used for the production of other related compounds with similar pharmacological properties. For example, the N-benzyl-4-methoxy-benzenesulfonamide coumarin derivative can be synthesized using lurasidone intermediate as a starting point. This coumarin derivative has also been shown to possess antipsychotic activity similar to that of lurasidone.

Overall, lurasidone intermediate is a critical compound in the production of lurasidone and related pharmacological compounds. Its properties and applications make it a valuable asset in the pharmaceutical industry, with the potential to advance treatment options for patients with mental health conditions.

Why choose Jianfeng lurasidone intermediate?

Jinan Jianfeng Chemical Co., Ltd. is a company headquartered in Jinan, China, which is specialized in the development, production and sales of pharmaceutical intermediates, APIs (active pharmaceutical ingredients), cosmetic raw materials and fine chemicals. The company has a state-of-the-art manufacturing facility and R&D center equipped with advanced technology and equipment to ensure high-quality products. Jinan Jianfeng Chemical Co., Ltd. has built a strong reputation in the industry with its dedication to quality, innovation and customer service. The company is committed to providing customers with safe and effective products that meet the highest quality standards and compliance.

Where to buy Jianfeng lurasidone intermediate?(buy lurasidone intermediate)

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