Ibrutinib N-3
CAS:330792-70-6
MF:C16H12N4O
MW:276.29
Sample: Available
Certificate: ISO,GMP,CTC,SGS,CQC
Place of Origin: Shandong, China
Lead time：1 working day after payment
Payment: T/T, Paypal, L/C,Western union
Description
Ibrutinib N-3 information:
| Product name | 5-aMino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile |
| Cas | 330792-70-6 |
| MF | C16H12N4O |
| Appearanc | Light yellow to off-white powder |
| Total impurity | ≤0.2% |
| Maxium single impurity | ≤1.0% |
| Residue on ignition | ≤0.2% |
| Heavy metals | ≤20ppm |
Ibrutinib N-3 Application:
3-Amino-5-(4-phenoxyphenyl)-4-cyano-1H-pyrazole is an intermediate used in the synthesis of ibrutinib, which is a Bruton's tyrosine kinase (BTK) inhibitor for the treatment of chronic lymphocytic leukemia (CChemicalbookLL) and mantle cell lymphoma (MCL). Ibrutinib can target BTK necessary for the formation, differentiation, information transmission and survival of B lymphocytes, irreversibly inhibit the activity of BTK, and effectively inhibit the proliferation and survival of tumor cells.
Ibrutinib N-3 Specification:
|
TESTS |
SPECIFICATIONS |
RESULTS |
|
|
Appearance |
Light yellow to off-white powder |
Off-white poeder |
|
|
Related substance |
Maxium single impurity |
≤1.0% |
0.33% |
|
Total impurity |
≤2.0% |
0.65% |
|
|
Loss on drying |
≤1.0% |
0.49% |
|
|
Residue on ignition |
≤0.2% |
Conforms |
|
|
Heavy metal |
≤20ppm |
Conforms |
|
|
Assay |
≥98.5% |
99.35% |
|
Ibrutinib intermediate cas 330792-70-6 will be packed in sealed plastic bags, and then be locked into fiber drum. But we could also pack it with aluminium foil bags to provide more protection to the goods as our customers' required.
Advantages
1. Supply sample
2. The packing also can be according the customers` requirement
3. Any inquiries will be replied within 24 hours4.we provide Commercial Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate. If your markets have any special requirements, let us know.
4. Factory price.
5.Prompt delivery. We have good cooperation with many professional forwarders, We can send the products to you once you confirm the order.
6.We can accept various payment methods, L/C, T/T, paypal, Western Union etc., and we cooperate with Jianfeng many years.
Contact us
Jinan Jianfeng Chemical Co.,Ltd
Fax: 0086-531-88113608
mail: info@pharmachemm.com
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