Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate
Apixaban Impurity B
CAS:27143-07-3
MF:C11H13ClN2O3
MW:256.69
EINECS:608-053-7
Mol File:27143-07-3.mol
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Description
Products Description
| Product Name: | Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate |
| Synonyms: | 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene];ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate;Apixaban Impurity B;(Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (Apixaban);Apixaban-2;1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide;Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester;Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate |
| CAS: | 27143-07-3 |
| MF: | C11H13ClN2O3 |
| MW: | 256.69 |
| EINECS: | 608-053-7 |
| Product Categories: | 27143-07-3 |
| Mol File: | 27143-07-3.mol |
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brief introduction
Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (CAS: 27143-07-3) is a raw material used as a pharmaceutical intermediate and, like other intermediates, is employed in the synthesis of APIs.
This compound is involved in Step 1, where the amine group on Compound 8 can undergo an acyl chloride amination reaction with 27143-07-3 to form a new compound.
Status: Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate is a key intermediate in the synthesis of apixaban api, and high-purity 07-3 intermediates have a high utilization rate.

COA
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Product Name: Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate |
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CAS No.:27143-07-3 |
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Batch No.:J-AP73-202504003 |
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Mfg Date: 20250423 |
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Retest Date: 202703 |
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Storage:Sealed, keep away from light. |
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Perform Standard: Enterprise Standard |
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Test Items |
Specifications |
Test Results |
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Appearance |
Light yellow to brown crystal |
Claybank crystal |
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Melting point |
98.0-101.2℃ |
Conforms |
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Loss on drying |
≤0.5% |
0.14% |
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Water |
≤0.5% |
0.01% |
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Residue on ignition |
≤0.2% |
0.02% |
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Residual solvents |
Methanol≤ 3000ppm |
38.57ppm |
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Acetone≤ 5000ppm |
2645.74ppm |
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2-Chloroacetyl acetate≤ 5100ppm |
0ppm |
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Related substances |
Single impurity :≤0.2% |
0.07% |
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Total impurities:≤1.0% |
0.29% |
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Purity(HPLC) |
≥99.0% |
99.71% |
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Conclusion: Conforms to Enterprise standard |
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Click to obtain the latest COA
Our factory &product



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| Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate | 27143-07-3 |
| 3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one | 536760-29-9 |
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Company Description
Company introduction
Jinan Jianfeng Chemical Co., Ltd. is a professional enterprise that integrates scientific research, production, and sales to produce chemical raw materials and intermediates.Relying on the business philosophy of "people-oriented and leading technology",the company has amassed a significant pool of cutting-edge talents from related industries, aligning itself with the global development trends in synthetic chemistry. Under this guidance, we consistently innovate and cultivate advantageous product varieties, both domestically and internationally, successfully exporting them to over 30 countries, including the United States, Germany, Canada, Japan, Russia, and Brazil, among others.



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