Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate
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Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate

Ethyl 2-chloro-2-(2-(4-Methoxyphenyl)hydrazono)acetate

Apixaban Impurity B
CAS:27143-07-3
MF:C11H13ClN2O3
MW:256.69
EINECS:608-053-7
Mol File:27143-07-3.mol
Similar Product:
536760-29-9
545445-44-1
503615-03-0
536759-91-8
503615-07-4
1267610-26-3
473927-63-8

Description

Products Description

 

Product Name: Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
Synonyms: 2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene];ethyl 2-chloro-2-[(4-methoxyphenyl)hydrazinylidene]acetate;Apixaban Impurity B;(Z)-Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (Apixaban);Apixaban-2;1-(4-methoxyphenyl)-4-(2-((4-(2-oxopiperidin-1-yl)phenyl)amino)ethyl)-1H-pyrazole-3,5-dicarboxamide;Chloro[(4-methoxyphenyl)hydrazono]acetic acid ethyl ester;Ethyl chloro[(4-methoxyphenyl)hydrazono]acetate
CAS: 27143-07-3
MF: C11H13ClN2O3
MW: 256.69
EINECS: 608-053-7
Product Categories: 27143-07-3
Mol File: 27143-07-3.mol

Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate Structure

 

 brief introduction

Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (CAS: 27143-07-3) is a raw material used as a pharmaceutical intermediate and, like other intermediates, is employed in the synthesis of APIs.

 

This compound is involved in Step 1, where the amine group on Compound 8 can undergo an acyl chloride amination reaction with 27143-07-3 to form a new compound.

 

Status: Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate is a key intermediate in the synthesis of apixaban api, and high-purity 07-3 intermediates have a high utilization rate.

Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate

COA

Product Name:

Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate

CAS No.:27143-07-3

Batch No.:J-AP73-202504003

Mfg Date: 20250423

Retest Date: 202703

Storage:Sealed, keep away from light.

Perform Standard: Enterprise Standard

Test Items

Specifications

Test Results

Appearance

Light yellow to brown crystal

Claybank crystal

Melting point

98.0-101.2℃

Conforms

Loss on drying

≤0.5%

0.14%

Water

≤0.5%

0.01%

Residue on ignition

≤0.2%

0.02%

Residual solvents

Methanol≤ 3000ppm

38.57ppm

 

Acetone≤ 5000ppm

2645.74ppm

 

2-Chloroacetyl acetate≤ 5100ppm

0ppm

Related substances

Single impurity :≤0.2%

0.07%

 

Total impurities:≤1.0%

0.29%

 Purity(HPLC)

≥99.0%

99.71%

Conclusion: Conforms to Enterprise standard

 

Click to obtain the latest COA

 

 
Our factory &product
 

 

Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
Picture one 
pharmaceutical intermediate cas 27143-07-3
picture two
Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate factory
our factory appearance

 

1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 503614-91-3
Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate 27143-07-3
3-Chloro-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one 536760-29-9
3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one 545445-44-1
3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one 503615-03-0
ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 536759-91-8
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 503615-07-4
1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone 1267610-26-3
Ethyl (2Z)-chloro[(4-methoxyphenyl)hydrazono]ethanoate 473927-63-8

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Company Description

 

 Company introduction

Jinan Jianfeng Chemical Co., Ltd. is a professional enterprise that integrates scientific research, production, and sales to produce chemical raw materials and intermediates.Relying on the business philosophy of "people-oriented and leading technology",the company has amassed a significant pool of cutting-edge talents from related industries, aligning itself with the global development trends in synthetic chemistry. Under this guidance, we consistently innovate and cultivate advantageous product varieties, both domestically and internationally, successfully exporting them to over 30 countries, including the United States, Germany, Canada, Japan, Russia, and Brazil, among others.

product-1772-1028

product-1772-1772

product-1772-1772

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