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![Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/uploads/202332977/ethyl-1-4-methoxyphenyl-6-4-nitrophenyl-724024843-677c-4cf7-9ad2-f3eed812fe7d.jpg)
Ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
Melting point:190-192°C
Boiling point:658.7±55.0 °C(Predicted)
density :1.40
vapor pressure:0Pa at 25℃
storage temp.:Sealed in dry,Room Temperature
solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
pka:-3.80±0.20(Predicted)
Description
What is apixaban intermediate CAS 536759-91-8 ？
Apixaban intermediate CAS 536759-91-8 is a pharmaceutical intermediate intended for the manufacture of the anticoagulant medication apixaban.
How to synthesize?
It is produced by a three-step synthetic process starting with 2,4,4-trimethylpentan-1-ol as the key starting material. First, it is condensed with 3-chloro-2-methylpropene to form an aldehyde, which is then reacted with 1-cyano-3-(4-ethoxycarbonyl-piperazin-1-yl)-propan-2-ol to form the desired intermediate.
The medical field use of apixaban is to reduce the risk of stroke and systemic embolism in adults with nonvalvular atrial fibrillation, to treat deep vein thrombosis and pulmonary embolism, to reduce the risk of recurrent deep vein thrombosis and pulmonary embolism, and to treat venous thromboembolism.
![ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/Content/uploads/2023786625/20230227151104ed7e408406f34a118a10cc08931bdc61.jpg?size=1772x0 "ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate")
![ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/Content/uploads/2023786625/20230227151034908e33e6afe74068be820ce0e3aa715e.jpg?size=1772x0 "ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate")
![ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate](/Content/uploads/2023786625/20230227151139bc789d0b1a974fb68378cff08cb768d4.jpg?size=1772x0 "ethyl 1-(4-methoxyphenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate")
About Jianfeng Chemical
The company has a team of experienced researchers and technicians who work in state-of-the-art laboratories to ensure the quality and purity of its products.
The company has obtained ISO9001:2015 certification, and its products are compliant with the international quality standards. Jinan Jianfeng Chemical Co., Ltd. exports its products to more than 50 countries and regions worldwide, including Europe, North America, South America, Asia, and Africa.
Jinan Jianfeng Chemical Co., Ltd. is committed to providing high-quality products and excellent customer service. The company strives to meet the needs of its customers by continuously improving its processes and procedures, as well as by investing in research and development to expand its product line.
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Contact
Email:sales01@pharmachemm.com
fax:0086-531-88113608
Adress: Province Shandong, China
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