NNMTi 5-amino-1MQ
NNMTi 5-amino-1MQ
CAS NO.:42464-96-0
Apparence:Reddish Brown Powder
Sample:Available
MOQ:1kg
Place of Origin: China (Mainland)
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Sample is Available
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COA, HPLC, MSDS available
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Description
NNMTi 5-amino-1MQ Basic Information
CAS No.: 42464-96-0
Chemical formula and specific structural information may vary depending on the source of detail, but the core components are the cation of 5-amino-1-methylquinoline and the iodide ion.
NNMTi 5-amino-1MQ Biological Functions
NNMTi (5-amino-1MQ) is a potent inhibitor of nicotinamide N-methyltransferase (NNMT) with an IC50 value of 1.2 μM, which means that it can effectively inhibit the activity of NNMT at low concentrations.NNMTi achieves its inhibitory effect by selectively binding to residues of the NNMT substrate binding site.
NNMTi has multiple beneficial effects:
Promoting myogenic cell differentiation: NNMTi can promote the differentiation of myogenic cells (e.g. C2C12 cells) in vitro, increasing the degree and efficiency of differentiation.
Enhancement of muscle stem cell fusion and regeneration: In an aged mouse model, NNMTi was able to activate and enhance the fusion and regeneration of muscle stem cells (muSCs), thereby improving the regeneration of aging skeletal muscle.
NNMTi 5-amino-1MQ Applications
NNMTi plays an important role in the regeneration process after muscle injury.
Able to improve muscle health, NNMTi has a great role in the fields of anti-aging, sports medicine and regenerative medicine.
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Jinan Jianfeng Chemical Co., Ltd.
Jinan Jianfeng Chemical Co., Ltd. is a pharmaceutical and chemical raw material research and development company, focusing on new biological drugs, APIs, pharmaceutical intermediates, cosmetic raw materials, daily supplements and other fields that promote human health. It has modern equipment and masters advanced natural fermentation and purification technology. The company mainly develops, produces and sells cosmetic raw materials and functional food supplements. For example, PQQ, NMN, coenzyme Q10, deazoflavin, etc.
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